The educational systems in the Piedmont Triad provide a trained workforce for businesses in the Region. This starts with the Region’s commitment to public education and ultimately extends to a superior community college system and eleven four-year colleges and universities.

The State of North Carolina and local communities in the Piedmont Triad have worked together to improve K-12 education in the Region. Some of the improvements seen in recent years include: Internet connections in virtually all classrooms; teacher-to-student ratios in elementary schools of 13-to-one, magnet schools, middle colleges and early colleges that provide excellent alternatives for students; ESL (English as a Second Language) programs at every level of education.

North Carolina’s New and Expanded Industry Training Program, available throughout the community college system, provides training for companies creating jobs in North Carolina. There are nine branches of the community college system in the Piedmont Triad, with 28 campuses and centers.

Piedmont Triad universities offering doctoral programs include UNC Greensboro, NC A&T University, Elon University and Wake Forest University. With the exception of Elon University, these schools are classified as research universities with "high research activity" by the Carnegie Foundation for the Advancement of Teaching.

North Carolina is a state focused on Research & Development. The Piedmont Triad Research Park and the Gateway University Research Park, located in the Piedmont Triad, are focused on regenerative medicine and nanotechnology applications. The Region is also proximate to the Research Triangle Park in Raleigh-Durham.